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Abstract Nigella sativa seeds are widely used by common people against many diseases. The present study was aimed to explore the effects of different levels of seeds on some hepatic and renal functions, and constituents of chicken muscle receiving Nigella sativa. Forty two clinically healthy, 30 days old Lohman chickens of both sexes were used in this study, and divided into six groups, seven birds for each. First group served as control, while the other groups received crushed Nigella sariva seeds in different concentrations (0.5, 1, 2, 4 and 8%) once daily for 36 successive days. Blood samples were collected after 21 days and 36 days along the experimental period. The serum was separated for determination of serum aminotransferases (SAST and SALT), alkaline phosphatase activity, bilirubin concentration, serum total proteins, serum albumin concentration, serum globulins and kidney function (urea, uric acid, and creatinine). As well as, liver and kidney specimens from each group were taken at the end of experiment to determine the histopathological changes after Nigella sativa administration. In addition, the Proximate analysis of chicken muscles receiving the seeds to determine their effects. |