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Abstract Ulcerative coliti is a chronic inflammatory bov el Disea e of unknown etiology though rare ill Egypt. There are fewer reports of ulcerative colin in the world literature, Most ha e hown II lightly higher incidence than for Crohn’s di ea. e and the incidence ha been unchanged over the last few decades Yamamoto-Furusho ef at., 2003). he incidence of lcerative coliti . has be n don by A systematic search of General practional clinical records in northern England, idenri ing ca e f inflammaro box el di ell. e. patient’ 011. tltati u bella iour. pre cribing pattern . lllldext’ent of speciali t care. In a population f 13-72’”’, ibe incidence of ulcerative c Iiti wa 13.91100000 per year and for Crohn’ disease 8.3/100 000 per year, The age-ex adjusted point prevalence for ulcerative colitis on it January 1995\ a 243.4/100000 and for Crohu’s disease 144.81100000. (Rubin GP. et (11.,2000). A recent study from tockholm 01) 1247 patients diagnos doer a 2.--year period shows a pattern imilar to that of rohn’s di ease” In this rudy the annual incidence of lcerstive coliti during the 1970 wa approximately IIIOO 000. during the 1980approximfltel 4VI00 000. and during the 1990 was approximstely 13/100000 It hA’ been a sumed that an inerea e Incidence i caused by the introduction of a nev infectiou agent to the ’environment. The opposite is pos ible; an increa e ill in idenc may be a reflection of au agent disappearing from the en ironment. I o. the increase ma be can ed by II decrease in population immunity rarh r Thall by 311 infectious agent. There ha been no attempt to demon rrate that one of thes hypotheses i more likely than th other (l’lOl’deuvall et at., 1995). |