الفهرس 
Diabetes with pregnancyOnly 14 pages are availabe for public view
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Abstract
Adiponectin is an adipose tissue, which is a specific plasma protein that is secreted by adipocytes. It is thought to play a role in the regulation of the glucose and lipid metabolism (Worda et al., 2004).
Adiponectin decreases the hepatic glucose production and insulin resistance by up-regulating fatty acid oxidation (Chandran et at., 2003). Adiponectin also suppresses the secretion of tumor necrosis factor-alpha by adipose tissue, which is a factor that is known to contribute to insulin resistance (Hotamisligil, 1999).
In other words adiponectin has emerged as an important potential mediator of the insulin resistance that is so characteristic of obesity, type 2 diabetes, and atherosclerotic cardiovascular disease (Ukkola & Santaniemi, 2002, and Berg et al., 2002).
It has been shown that adiponectin serum levels were decreased in obese subjects (Arita et al., 1999) and patients with type 2 diabetes mellitus (DM2) (Weyer et al., 2001). Adiponectin plasma levels decrease with progression of obesity and insulin resistance (Hotta et al., 2001).
Moreover, low baseline adiponectin concentration predicts the subsequent development of insulin resistance (Stefan et al., 2002, and Retnakaran et al.,2004).