الفهرس 
EpilepsyOnly 14 pages are availabe for public view
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Abstract
Temporal lobe epilepsy (TLE) is a multifactorial disease often involving the hippocampus. So far the etiology of the disease has remained elusive.
Magnetic resonance imaging (MRI) is an attractive tool to identify the presence and development of cerebral damage in patients with epilepsy as it is readily available, non invasive, and acceptable to the patients.
The concept that the immune system plays a role in the epileptogenic process of some epileptic syndromes was first proposed more than 20 years ago. Since then, numerous studies have reported on the existence of a variety of immunological alterations in epileptic CIC participation in the pathogenesis of some disease has been established, but its role in epileptogenesis and other aspects of epilepsy was not fully investigated.
Hence, the aims of this work were: 1- to assess the role of CIC-C3b in temporal lobe epilepsy and its relation to different clinical and radiological aspects of TLE. 2-to study the changes in the temporal lobe and the hippocampus using magnetic resonance imaging in patients with TLE and to correlate these changes to the clinical and immunological data obtained.
This study was a case control cross-sectional study which was conducted on 50 children and adolescents with TLE following up in the Pediatrics Hospital’s Neurology Clinic, Ain Shams University.