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Abstract The study was conducted on a group of cancer patients attending the out-patient clinics of the National Cancer Institute, Cairo University to evaluate the food consumption pattern and the alteration in lipid metabolism in different malignancies. Six groups of cancer patients were included as well as a matched control group. The groups were breast cancer, Hodgkin’s disease (HD), non-Hodgkin’s lymphoma (NHL), chronic myeloid leukemia (CML), chronic lymphocytic leukemia (CLL) and bladder cancer. Clinical examination and anthropometric measurements were done. Also, food consumption pattern was assessed. Serum lipid pattern was estimated including: TGs, total cholesterol, total lipids, HDL-C, LDL-C, VLDL-C, apo A1, apo B, PGE2, lipid peroxide (malondialdhyde) and differential fatty acid pattern. Some changes were found in the analyzed parameters. There was an elevation in levels of TGs, VLDL-C, apo B, lipid peroxide and the serum PUFAs (arachidonic acid, EPA and DHA). Also, it was found that patients included in this study did not obtain adequate calorie intake, their diet was poor in fiber content and most of them did not consume extra fat than normal, but their diet contained relatively low amounts of ω-3 fatty acids. The state of hypertriglyceremia and the relatively increased very low density lipoprotein cholesterol prevalent among those patients must be handled in proper time to avoid health hazards. |