الفهرس 
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Abstract
The initial pathologic change in RA is believed to occur in small blood vessels. However, it is useful to use the term vasculitis to group those extra-articular complications related not to proliferative granulomas but rather to inflammatory vascular disease (Harris 2001).
Rheumatoid vasculitis has several clinical presentations, which can be sometimes difficult to diagnose. Inflammation of small and medium sized vessels can cause skin disorders such as rash, cutaneous ulcerations and gangrene, neuropathy, eye symptoms and may also affects visceral organs (Verschueren et al., 2000).
As regard genetic suceptibility to rheumatoid vasculitis (RV). It was found that the population with HLA-DRB1* 0405-DQA1* 0301 – DQB1* 0401 haplotype was associated with the susceptibility to rheumatoid arthritis (RA) (Nishimura, 1994).
In systemic rheumatoid vasculitis there is unusual DQA-DR haplotypes, DQB*0302 rather than DQB*0301 was increased in frequency in rheumatoid vasculitis (Harris, 1997).