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Abstract In the light of this, the present work aimed to detect the frequency and prognostic significance of TEI-AMLI fusion gene among Egyptian childhood b-lineage acute lymphoblastic leukemia, and to evaluate FISH and PCR as methods for detection of this translocation. Peripheral blood were obtained from 50 children suffering from ALL 9all of them were newly diagnosed). After culture technique and RNa extraction, only 29 patients were available and all were subjected to the following: * Full history and thorough clinical examination. * CBC. * Bone marrow aspiration. |