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Abstract Venous thromboembolic disease (VTE) is common condition, with clinically recognized deep vein thrombosis (DVT). Patients with chronic liver diseases are at risk of developing venous thrombosis. Portal vein thrombosis was detected in 7% and DVT in 5.5%. this could be attributed protein C and protein S. In fact, in cirrhotic livers obstruction of small intrahepatic portal hepatic veins is observed almost invariably. Thus changes in the composition of the blood towards a hypercoagulable state in combination with changes in the endothelium of intrahepatic vessels and/or in intrahepatic blood flow, which often develop in chronic liver disease with fibrosis, certainly favour the development of thrombosis in intrahepatic veins. The present work has signified the role of the chronic liver disease as a risk factor of venous thromboembolism. |