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Abstract
Helicobacter pylori is one of the most common bacterial pathogens in humans. H. pylori is now recognized as a world wide problem. It causes chronic gastritis, peptic ulcer disease, and lymphoproliferative disorders and is a major risk factor for gastric cancer (Crew et al.,2006).
Portal hypertensive gastropathy defines a pathological endoscopic picture characterized by the presence of alteration of the gastric mucosa found in patients with hepatopathy associated to an initial or evident portal hypertension. The role of H. Pylori in the development of these alterations, in terms of prevalence of infection in hepatopathic subjects is still controversial (Urso et al., 2006).
Portal hypertensive gastropathy is the most common gastric mucosal injury to patients with liver cirrhosis. The main histological change is that blood vessels in the mucosa and sub mucosa become dilated and twisted, and the vessel wall become thickened. In fact, PHG is the major factor in patients with liver cirrhosis who were accompanied with upper gastrointestinal haemorrhage (Bayraktar, et al., 1996).