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Abstract
Advanced imaging modalities and use of different contrast media in MRI play an important role in characterization of focal hepatic lesions in non-invasive fashion.
Magnetic resonance imaging is a powerful tool in the evaluation of liver neoplasms. It has many advantages including; high soft tissue contrast resolution, tissue characterization, technical versatility for sequence selection and modification, multiplanar imaging, intrinsic sensitivity to blood flow and blood breakdown products, as well as lack of ionizing radiation. In addition, magnetic resonance imaging proved to be more sensitive than contrast enhanced computed tomography for detection of mass in the liver.
Imaging of focal liver lesions has progressed enormously with the development of MRI technology and contrast agents. Modern MRI with update sequences and contrast agents is non-invasive and highly accurate in examining patients with known or suspected liver lesions. Contrast agents provide another tool for improving the performance of MRI in liver lesion detection and characterization. Since tumors of the liver exhibit variable appearances on MR. the key to accurately detecting and characterizing liver lesions is the proper use of the variety of MR contrast agents now available for clinical use. An understanding of the underlying pathology and histology of liver tumors and how these affect the appearance on unenhanced and contrast enhanced MR images is also important in order to optimize its diagnostic potential.