الفهرس 
LITERATURE REVIEWOnly 14 pages are availabe for public view
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Abstract
With the earths increasing nuclear arsenal and the growing use of nuclear energy, the possibility of radiological accidents involving release of radioactive materials, internal contamination may consequently occurs via inhalation, ingestion or absorption of radioisotopes.
Therefore, the present work was oriented to deal with four topics related to the internal decontamination of two of the most widely used isotopes, namely 134Cs and 60Co from contaminated rats:
• In vitro study aimed to select agents that can strongly bind the two metal ions and elucidate the best conditions and the factors affecting this binding. The tested agents were bentonite, vermiculite and Prussian blue (PB). The sorption capacity of PB and vermiculite for both metal ions was high and equivalent to more than 1011 Bq 137Cs or 60Co per gram sorbent. As bentonite has lower capacity to both isotopes, further in vivo experiments were performed with PB and vermiculite.
• In vivo studies, via 5 groups of rats, devoted to investigate the kinetics of excretion of 134Cs and/or 60Co from contaminated rats. The biological half lives of excretion, excretion stages for both isotopes and the effect of route of entry on the excretion were estimated.
• In vivo studies aimed to investigate the effectiveness of PB+vermiculite and CaDTPA as therapeutic agents for accelerating the elimination of 134Cs and/or 60Co from contaminated rats. The study was performed via 6 groups of rats given different regimes of therapy. The results showed the high efficiency of PB+vermiculite for accelerating elimination of 134Cs and orally administrated 60Co while CaDTPA succeeded in accelerating intraperitoneally administrated 60Co. The study proved that oral administration of PB+vermiculite and injection with CaDTPA at the same time is very effective in accelerating elimination of both contaminants simultaneously.