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Abstract
* Liver function tests ( ALT, AST and bilirubin) can not be used
as a reliable marker of HGV infection in multiply - transfused
patients.
* HGV coinfection probably does not have a significant effect on
hepatitis C virus - induced hepatic injury.
Thus, this study revealed that the multiply - transfused patients
ill our locality are at high risk for HGV infection. However, despite
the high rate of HGV transmission, it has not been found to be a
predominant cause of transfusion associated non-A-E hepatitis
therefore, if a significant liver disease and/or any other disorders
associated with HGV infection is established, it will be necessary to
develop a practical screening assay to exclude HGV infection from
the donors blood . The development of such test system is a matter
of urgency smce mass screening of blood donors, usmg the PCR
technique is highly impractical at present, although it is the most
sensitive method.