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Abstract Anovulation associated with PCOS has long been known to be amenable to surgical treatment, and a recent long-term cohort study up to 20 years after laparoscopic ovarian electrocautery has shown persistence of ovulation and normalisation of serum androgens and SHBG over many years in over 60% of subjects. Insulin resistance and serum lipids were not assessed, but women with PCOS treated with ovarian diathermy for reproductive reasons might obtain long-term benefit over and above resumption of ovulation and menses. The long-term benefits of ovarian drilling, including alterations in endocrine profile, have recently been confirmed in a second publication. However, at present, the risks of surgery do not justify recommendation of this treatment purely in an attempt to ameliorate the chances of developing diabetes or coronary artery disease in later life. |