الفهرس 
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Abstract
The aim of the evaluate the efficacy of nitric oxide donor, glyceryl trinitrate, (angised) as cervical ripening agent before termination of second trimester pregnancy.
Conclusion:
1- Misoprostol is less effective drug in induction of second trimester pregnancy termination in patients with unfavourable cervix (Bishop Score < 4) because of nearly half cases need complementary procedures and only half of these patients completed termination of their pregnancy without any complementary procedure.
2- NO donor glyceryl trinitrate was effective drug concerning cervical ripening as regard it improves the Bishop score on repeated doses.
Recommendations:
1- NO donor can induce more cervical ripening by local application of gel or past intra-cervical. This may produce more significant changes in Bishop Score and be more effective as cervical ripening agent.
2- Use of other systemic preparations of NO donors as Isosorbid mononitrate instead of glyceryl trinitrate for higher doses.
3- Glyceryl trinitrate can be used with higher doses to produce more cervical ripening effect.
4- The NO donor can be also used for produce more softness of the cervix before suction evacuation of vesicular mole.