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العنوان
Quantitation Of Certain Carboxylate Derivatives In Phytopharmaceuticals/
المؤلف
Barghouth, Neveen Mohammed Hussein.
هيئة الاعداد
مشرف / عبد العظيم حبيب
مشرف / فتح الله حراز
مشرف / نجوى الشاعر
باحث / نيفين محمد حسين برغوت
الموضوع
Pharmacognosy.
تاريخ النشر
2006 .
عدد الصفحات
107 p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/2006
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - Pharmacognosy
الفهرس
Only 14 pages are availabe for public view

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from 144

Abstract

Basic Background study on the difference spectra of the target compounds (reserpine and yohimbine)
This part describes the basic principles of the difference spectrophotometry and its importance. It also includes the difference absorbance spectra used in this thesis, determination of maxima (MAX), minima (MIN) and isosbestic points (ISO) in all of these spectra. Deduction of the correction factors used in the calculations is also presented.
Part II
Quantitative determination of reserpine in pharmaceutical preparations
This part presents two different techniques for the determination of reserpine in pharmaceutical preparations
I- Determination of reserpine and rescinnamine by difference spectrophotometry
The method was carried out by alkaline hydrolysis of the alkaloids; the difference absorbance spectra of the liberated acids (reserpic acid and TMB in case of reserpine and TMC in case of rescinnamine) were recorded in acidic versus in alkaline solutions. It was found that the hydrolytic products of some tablets ingredient.