الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
Addition of cholesterol may increase or decrease the entrapment efficiency of the
prepared niosomes, depending on method of preparation and structure of surfactant used.
2- Span 60 formulations showed higher entrapment efficiency and higher release of drug.
3- Particle size distribution studies revealed that formulations prepared without
cholesterol, showed the smallest particle size. However, increased particle size was obtained
by increasing cholesterol molar ratio, using FHM and in formulations prepared using Span 60.
4- Most niosomal formulations showed lower permeation rate compared to drug solution,
except formulations 3A, 3B and 8B which correspond to the 1:1 cholesterol surfactant molar
ratio.
5- Corneal hydration studies showed .