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العنوان
Ovarian volume assessment by three dimensional ultrasound in polycystic ovarian disease and its correlation to hormonal profile/
الناشر
Alex uni F.O.Medicine ,
المؤلف
El Sayed, Ola Lotfy Mohamed
هيئة الاعداد
باحث / علا لطفى محمد السيد
مشرف / فوزية محمود محمد صالح
مشرف / محمود على عبد النبى محمود
مشرف / احمد محمد عبد العزيز رزق
مشرف / امل زكى احمد عزام
الموضوع
Obstetrics & gynecology
تاريخ النشر
2008
عدد الصفحات
68p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2008
مكان الإجازة
جامعة الاسكندريه - كلية الطب - امراض النساء والتوليد
الفهرس
Only 14 pages are availabe for public view

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Abstract

Polycystic ovarian syndrome (PCOS) is one of the most common human endocrinopathies, its diagnosis was previously based on clinical and endocrinal examination only, but after the introduction of pelvic ultrasound in the 1980s, non-invasive assessment of ovarian morphology became possible, and recently the ultrasound diagnosis of PCO was considered as one of the diagnostic criteria of PCOS beside the endocrinal and clinical features.
This study was conducted to compare between ovarian volume measured by two-dimensional and three-dimensional transvaginal ultrasound, also to correlate these measurements with some hormonal status of 30 selected polycystic ovarian syndrome (PCOS) patients.
Those 30 selected PCOS patients were recruited from the out patient clinic of El-Shatby University Maternity Hospital.
All patients were examined and evaluated on the 3rd or 4th day of their spontaneous menstruation or at any time if amenorrhea was present considering that they had not received any hormonal medication or subjected to ovarian hyperstimulation regimen for at least three months prior to the study.
Full history taking, thorough clinical examination and calculation of the patients body mass index were done, also basal serum hormonal analysis for (FSH, LH, prolactin, E2, total and free testosterone) was carried out.
Transvaginal ultrasound for each patient was carried out to exclude any genital or pelvic pathology, to assess the ovarian morphology regarding the stromal echogenicity and to dermine the number, diameter and the distribution of the microcytes. Also, it was used to measure each ovarian dimensions to calculate the ovarian volume. Measuring the endometrial thickness and the uterine diameters for calculation of the uterine volume was done. Exclusion of ovulation was confirmed by extended ovarian folliculometry or by measuring the midluteal serum progstrone (3 ng/ml).
The patients mean age was 27.04.54 years, their mean body mass index was 33.65.40 kg/m2. Infertility was the main presenting symptom, (51.7%) presented with hirsutism.
It was found that there is a statistically significant difference between ovarian volume measured by 2 dimensional transvaginal ultrasound and 3 dimensional transvaginal ultrasound.
There was a positive significant correlation between body mass index and free-testosterone, and there was a negative significant correlation between body mass Index and LH. No significant difference in total testosterone levels, E2 , prolactin hormone, FSH was found between obese and lean PCOS women.
There was a positive significant correlation between ovarian volume (measured by 3D-US) and E2, total testosterone hormone. But no significant correlation between the ovarian volume and prolactin hormone, f-testosterone hormone, LH, FSH.
No, statistically significant correlation was found between BMI and ovarian volume measured by 3D-US.
No statistically significant correlation was found between androgenic manifestations (hirsutism, acne) and BMI, also no significant statistical correlation between androgenic manifestations and ovarian volume