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Abstract
The present study, was carried out on 420 fish of Clarias gariepinus, they
were collected from Ismailia governorate and investigated for internal parasitic
diseases The clinical signs of internal parasitic diseases revealed no pathognomonic
signs There were some clinical signs like emaciation, anemia, skin colour
f1actuation, and abdominal distension. The parasitological examination of infested
fish revealed adult trematodes from the intestine metacercariae from the
musculature and liver Cestodes and nematodes from the intestines. The total
prevalence among examined catfish Clarias gariepinus was 73.80% . The higher
seasonal prevalence was in summer while the lowest was in winter The histopathological
changes of the intestines, liver and musclature were recorded as necrotic enteritis,
tickening and odema of submucosa and infiltration of inflammatory cells Numerous
encysted metacerearia were embedded among the muscle bundles. The hepatic
paranchyma showed numerous parasitic cystes .