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Abstract Aim of the work To evaluate some aspects of mineral metabolism and bony changes in children with chronic renal failure and nephrotic syndrome in comparison to normal children. Conclusion Our study showed hypocalcemia, hyperparathyroidism in both CRF and NS while alkaline phosphatase enzyme activity was increased in both groups and lastly bone densitometry decreased in NS and increased in CRF. So, more studies are needed for accurate correlation between calcaemia action of PTH in NS and the vitamin D metabolites and for accurate correlation between bAP and bone changes in renal diseases and for better correlation between bone density and secondary hyperparathyroidism in renal diseases in children. |