الفهرس 
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Abstract
Aim of the work
To detect chromosomal abnormalities in patients suffering from epilepsy through chromosomal study of metaphases by the use of G-Banding technique. And also evaluate correlation between these results and physical malformation and intellectual disabilities.
Summary
This study was included 50 subjects divided into:
Group 1: 20 epileptic patients, with normal mental and physical developments.
Group 2: 30 epileptic patients suffering from intellectual disabilities and or dysmorphic features.
- All participants were subjected to complete history, careful general and neurological examination, electroencephalopathy, computerized tomography and chromosomal karyotyping.
Cases with secondary epileptic were excluded from this current study. In this study we found that:
- All cases of group 1 had normal chromosomal complement.
- Four cases of group 2 had chromosomal complement 1st had small deletion of the long arm of chromosomal, 2nd has ring chromosome, 3rd and 4th cases had terminal deletion of the long arm of chromosome 6.
Our results corroborated the view that:
1- No abnormalities of chromosomal pattern in cases with normal epileptic patient.
2- Certain chromosomal aberration can be identified in the intellectually disabled patient and/or patient with dysmorphic features.