الفهرس 
Introduction and Aim of The WorkOnly 14 pages are availabe for public view
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Abstract
Aim of the work
To compare the safety and efficacy of bupivacaine alone, sufentanil alone or combined bupivacaine and sufentanil through caudal blockade, in a blind, controlled and randomized study to provide postoperative analgesia in pediatric patients.
Results
The results of this study showed that in group I , there were significant decrease in hemodynamic data and respiratory rate after 30 minutes with significant increase in end-tidal CO2 and mean duration of analgesia of about 9.5 +(-)4.8 hours. According to the pain scores, there were significant decrease in pain intensity score with less sedation less motor block and high sensory level.
In group II, the onset of significant decrease in the hemodynamic variables started within 15 minutes. The mean duration of analgesia was about 5.0+ (-) 1.3 hours and there were increases in the percentage of requirements for other analgesic drugs. According to the pain scores, there were insignificant reduction in pain intensity score and there were no reported cases of respiratory depression with mild sedation and acceptable sensory level.
In group III, there were significant decreases of hemodynamic variables after about half an hour of injection and long duration of analgesia of about 17.4+ (-) 7.0 hours with the least percentage of the requirements for other analgesic drugs. There were significant decreases in pain scores with moderate sedation, high sensory level and less motor block.
From this study, we conclude that all the three methods are simple, safe and effective for postoperative pain relief in pediatric patients. But the combined effects of bupivacaine and sufentanil provide the most effective analgesia of a good quality and of a longer duration than the use of a single drug.