الفهرس 
INTRODUCTION AND AIM OF THE WORKOnly 14 pages are availabe for public view
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Abstract
Aim of the work
To compare the effects of halothane versus isoflurane on the liver functions in patients previously exposed to general anesthesia with halothane within the previous year and in patients exposed to these anesthetics for the first time.
Results
In the two groups of patients that were exposed to halothane or isoflurane for the first time, halothane produced more significant changes in ALT, AST, alkaline phosphate and coagulation factor VII concentration than isoflurane.
These changes were more pronounced on the first post operative day and some of them returned to nearly the base line value after one week.
Meanwhile, both halothane and isoflurane produced no significant changes in plasma proteins, serum bilirubin or prothrombin concentration.
In the two groups that have been exposed to halothane within the previous year, halothane produced significant changes ALT, AST, alkaline phosphate, prothrombin concentration and coagulation factor VII. Meanwhile isoflurane produced significant changes in AST and alkaline phosphate only.
Conclusion
In conclusion; it is safety to say that halothane has definite effects on the liver compared with isoflurane and that effects are more pronounced with re exposure to halothane anesthesia. However, some of these effects are reversible within one week.