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العنوان
Clonidine versus Midazolam for Premedication in Pediatric Surgery
الناشر
Mohamed Sabra Abdellah ,
المؤلف
Abdellah, Mohamed Sabra
هيئة الاعداد
باحث / Mohamed Sabra Abdellah
مشرف / Ibrahim Talaat Ibrahim
مشرف / Nagy Sayed Ali
مشرف / Khaled Ahmed Abdo
الموضوع
Anesthesia Pediatric Sedation Postoperative Pain Managment in Children Pharmacology of Clonidine Pharmacology of Midazolam
تاريخ النشر
2005 .
عدد الصفحات
137 p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة المنيا - كلية الطب - anesthesiology
الفهرس
Only 14 pages are availabe for public view

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from 147

Abstract

Aim of the work

To evaluate the effects of rectal midazolam in comparison with rectal clonidine for premedication in pediatric surgery, as regard to the level of sedation, anxiolysis, hemodynamic stability, postoperative analgesia and side effects in a double-blinded randomized study.
Conclusion
We conclude that, rectal midazolam (300ug/kg) is superior to rectal clonidine (5ug/kg) as a pre anesthetic medication in children, because it produced more rapid and effective pre-operative sedation with better response to parent separation and mask application and obvious hemodynamic stability. As regard the post operative outcomes, clonidine seemed to have early postoperative analgesia, more prolonged postoperative sedation, less postoperative sevofluraine induced confusion, less incidence of shivering, nausea and vomiting.
Recommendations
We recommend further studies using combinations of rectal clonidine and midazolam, to get the benefits of pre-operative sedation and anxiolysis of midazolam and preferable postoperative outcomes of clonidine.