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Abstract
Hepatocellular carcinoma is one of the most serious problems worldwide. HCC accounts for 90% of primary liver cancers and causes at least 1 million deaths worldwide per year. It is the 5th most common cancer in the world and the 4th in annular mortality.
In the majority of cases, HCC is found in conjunction with cirrhosis of the liver. The underlying liver cirrhosis is not only a major obstacle for achieving successful treatment for HCC but also a protruding factor promoting intrahepatic invasion and metastasis of HCC.
Accurate diagnosis of neoplastic lesions by means of one or more imaging modalities (ultrasound, US; computed tomography, CT; and magnetic resonance, MR) is mandatory.
Surgical resection remains the only potentially curative treatment of hepatic malignancies. Unfortunately, most primary and secondary hepatic malignancies are unresectable.
The present study included 10 patients with hepatocellular carcinoma treated in vascular and interventional unit, Radiology department, Zagazig University Hospitals; Patients were treated with transarterial chemoembolization.
In the present study, age ranged from 34-76 years, males were more affected than females with a male: female ratio of 4:1.
According to ECOG performance status, 40 %of the cases were scale 0, 50% were scale I and 10 % scale II.
Tissue diagnosis is present in 40% of the cases. AFP level above 1000 ng/ml was considered enough for diagnosis in remaining patients.
Most of the patients had single nodular tumor (50%) followed by multinodular tumors in 30% and lastly massive type in 20%.
All patients had tumors larger than 5 cm in size .and most of cases, tumor ranging from 5-10 cm.
Child B was more encountered (60%) and child A (40%) ,stage III on TNM classification is more encountered in 70% of the cases .On the other hand ,stage I Okuda disease was more found (70%.