![]() | Only 14 pages are availabe for public view |
Abstract SUMMARY AND CONCLUSIONS Secretory otitis media and chronic suppurative otitis media media are common diseases in the field of otolaryngology. Eustachian tube has a major role in pathogenesis of both conditions. Cytological study of the eustachian tube can help us to know whether any pathological changes occur in the tubal mucosa during the course of secretory and chronic suppurative otitis media. Our study included 20 healthy persons as a control group, 20 cases with secretory otitis media and 20 cases with chronic suppurative otitis media. All cases were examined clinically by pure tone aUdiometry and and aUdiologically typmpanometry. assessed The pharyngeal orifice of eustachian tube was swabed with the patients under general anaesthesia, in the tonsillectomy position. Dry wipe technique was used with 71 the aid of fibreoptic nasopharyngoscope. The swabs were smeared on glass slides, fixed by absolute alcohol and stained by Papanicoloau stain. The slides were scanned by x 400. Each slide was examined for at least 10 minutes. Normal controls showed columnar ciliated cells and goblet cells, but no plasma cells, metaplastic cells, or histiocytes could be detected. Cases with secretory otitis media showed increase in columnar and goblet cells indicating hyperplasia of the tubal mucosa with proliferation of goblet cells. Few metaplastic cells were detected with increase in leukocytic infiltration, and appearance of plasma cells, indicating presence of infection with increase thickness of tubal mucosa. Cases with chronic suppurative otitis media showed marked increase in ciliated and non ciliated columnar cells with infiltration of plasma cells and histiocytes. this is an indication of chronic suppurative infection. from this results we can conclude that eustachian tube is not just a passive conduit between the tympanic 72 cavity and the nasopharynx, but its mucosa undergoes the same pathological changes as mucosa of the tympanic cavity during the course of secretory and chronic suppurative otitis media, but to a lesser extent. This changes may be the cause or the result of the pathological changes in the tympanic cavity and antrum. so, study of the tubal mucosa can give an idea about the condition of the middle ear mucosa. 73 ---~~- --- -- ----- |