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العنوان
Influence of Different Statins on the Ability of Clopidogrel to Inhibit Platelet Aggregation in Patients with Unstable Angina
الناشر
Mahmoud Mohamed Shehata ,
المؤلف
Shehata, Mahmoud Mohamed
هيئة الاعداد
باحث / Mahmoud Mohamed Shehata
مشرف / Nasser Mohamed Taha
مشرف / Adel H. Mahmoud
مشرف / Ayman G. Ghobrial
الموضوع
Cardiology Unstable Angina Clopidogrel
تاريخ النشر
2005 .
عدد الصفحات
129 p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة المنيا - كلية الطب - أمراض القلب
الفهرس
Only 14 pages are availabe for public view

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Abstract

Aim of the work
The aim of this study is to clarify the influence of Atorvastatin, Pravastatin and Fluvastatin on the ability of Clopidogrel to inhibit platelet aggregation in patients with unstable angina.
Conclusion
Our study demonstrated that:
1- Atorvastatin, but not Pravastatin, nor Fluvastatin attenuated the anti platelet activity of clopidogrel.
2- Attenuation of the anti platelet activity of clopidogrel after loading dose 300mg is statistically significant among all study groups. But this statistically significant difference was of lower value in group 2 (Atorvastatin group).
3- Co administration of diltiazem attenuated that anti platelet activity of clopidogrel.