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العنوان
Role of specific antiamoebic lectin antibodies in differentia tion of entamoeba histolytica frome. disparin A seroepidemiological study /
المؤلف
Hassan, Manal Ibrahim.
الموضوع
Antibodies. Entamoeba histolytica.
تاريخ النشر
2005.
عدد الصفحات
130 p. :
الفهرس
Only 14 pages are availabe for public view

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Abstract

The true epidemiology of Ehistolytica remains unknown because
1110st of the existing data were collected using methods incapable of
distinguishing Ehistolytica from E.dispar (Huston &Petri, 1998). So
WHO (1997a) Prioritized the need to accurate prevalence data for
Ehistolytica. The present study took for getting insights into the
prevalence and other c1inico epidemiologic data on Ehistolytica infection
in EL-Moreig village, Qalyobia govemorate in the Delta of Egypt.
The study used ELlSA technique to detect antibodies to
E.histolytica Gal/Gal NAc lectin in the sera of a population sample of
148 individuals selected on their consent by the stratified random method.
The contributing individuals were also subjected to history taking and
thorough medical examination and coprotesting for ova and parasites and
for occult blood. The diarrhoeal cases were treated empirically by specific
antiamoebic drug (Mitronidazole). The amoebic cases were identified
according to coprologic, serologic, clinical and therapeutic criteria.
Results and conclusion
1- The study showed wide prevalence of intestinal parasites that are faeco-
orally transmitted.
2- The overall seroprevalence was 18.9% compared with 32.4%
microscopic coproprevalence.
3- The seropositivity rates significantly correlated positively with age.
This correlation was lost as regards copropositivity rates.
4- The study showed insignificant difference in the seropositivety rates
among both the copropositive and copronegative individuals. The
same situation was recorded as regard copropositive among
seropositive and seronegative individuals, this referred to a state of
endemicity and lack or insufficient immunity to this protozoan.