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Abstract The aim of our work in this part of the thesis is to synthesise some triazino-indoles of biological interest through cyclization reactions of 3-hydrazino- triazino [5,6-b] indole (3) with Nitrous acid (Nano2 / H3Po4) afforded azide (64) wich Could be cyclized with acetic anhydride to give (63b). Also Treatment of (3) with (Nano2 / conc. HC1) gave the Corresponding tetrazole Compound (63a). Refluxing (3) with 1-naphthaldehyde and/or benzal-dehyde in absciute ethanol gave (69a) and (69b) respectively, while refluxing (3) with 1-naphthaldehyde and/or p-nitrobenzaldehde in acetic acid yielded the Corresponding (70 a) and (70 p) respectively. Reaction of (3) eith dicarbony 1 Compound was assumed to involve one or both of the carbony1 reagent condinsations. thus heating eguimolar amounts of (3) and diacety1 in ethanol eave only the Corresponding monohydrazone (71). however in the presence of excess of (3) in galcial acetic acid the Corresopnding dihydrazone (72) was Produced. |