الفهرس 
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Abstract
The role of histamine, serotonin and catecholainines in
SO experimental pathological conditions was investigated , using the rat. The experimental pathological conditions in— 1vestigatedere : in±’lanniation induced by cotton pellets implantation, insulin h,ypoglycemia and alloxan diabetes, castration and ovriectomy, and carbon tetrachioride hepatotoxicity. The following results have been observed :
1.- Glandular stomach histidine decarboxylasa activity
1was markedly increased by insulin hypoglycemia. The maximal
fect of insu].:.n on this enzyme was observed between 4 and 6 after insulin administration. On the other band, aJioxan
diabetes decreased the activity of the enzyme • Inflammation Ld by cotton pellets implantation in the groins and. azcillae,
d carbon tetrachioride hepatotoxicity, caused an increase in activity of the histidine decarboxylase.
2- Intestinal histamiriase (Diamine oxidase) was markedly ncreased in inflammation, not markedly changed in insulin og1ycemia, alloxan diabetes, carbon tetracbloride hepato— oity and ovariectomy, but markedly decreased by castration.
3- Urinary free histamine output was not changed in
ion but significantly decreased in alloxan diabetes.