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Abstract The aim of this work is to review the literature on the subject maldescended testis and to study clinical, histopathological changes and different lines of treatment of these cases at different age groups, because this anomaly needs to be more widely understood, accurately diagnosed and effectively treated at appropriate time. Our results shows that the degenerative changes which showed by E.M. were appear in the biopsies of boys 2 years old despite the minimal or no findings by L.M. in same age group. For ethical reasons, access to healthy testicular biopsies is extremely limited and therefore we were not able to compare the cryptorchid testes with normal testicular biopsies or other contralateral descended testis. So, we can’t prove that, whether the known changes in the cryptorchid testis represent a primary defect or only an alteration secondary to cryptorchid state. Support for the idea that the testis itself is detective lies in the observation that some of these histologic changes May also occurs in the contralateral scrotal testis of the unilateral cryptorchid male. |