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Abstract Aim of the work To detect the prevalence of hepatitis C in infants and children who received single transfusion and multi-transfused. Multi-transfused children are those who had received two or more units of blood. Conclusion Our study showed the incidence of hepatitis C virus antibodies in the range of that reported in different studies in Egypt and this may be attributed to that HCV antibody screening was not yet available in Egyptian blood banks. In our study, HBSAg detection was in the range of that reported in Egypt in different studies and this is attributed to less exposure of cases to infection and recent proper screening of blood and blood products for hepatitis B. Also, in our study there is increasing incidence of HCV with the increasing frequency of blood transfusions and decreasing incidence of HBSAg detection, as HCV infection leads to clearing of HBV antigeneamia. Also, this study proved that the risk for HCV infection increased to the number of blood units received. |