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Abstract
Aim of work is To determine the different patterns of glomerular lesions in Egyptian patients. We will search for any correlation between clinical signs and histopathology of renal biopsies of the studied patients. The emphasis of clinical picture, laboratory data or histopathology on prognosis will be investigated one year after appropriate treatment.
dentrncation of ti1e profile of glomerular disease in a particular geographic region is of grear academic, clinical and epidemiological importance. It helps recognition Df the specific risk factors and allows for subsequent planning for adequate prevention. In this study, we examined 84 patients with renal biopsy diagnosis of GN, we followed them for
at least a year. They were 38 females (45..2%) and 46 males (54.8%). The mean age was 29.9 ± 12.1 years. The primary glomerulaopathies constituted 71.4%. The secondary GNs 143% and the non GN 143% of the total number of patients (non GN: tubulointerstitial disease, amyloidosis and nephrosclerosis). The different proportions of primary
GNs were: Mes P 22.6% (19 patients), MPGN-MGN 1L9% (10 patients each~ focal proliferative and FSGS 7%) each (6 patients), the proliferative GN 6% (5 patients), MCD 4.8% (4 patients). A positive correlation between age and last mean serum creatinine and initial proteinuria. Males showed better creatinine and proteinuria prognosis than females. Prevalence of HTN was 47.6% (40 patients). It was associated with greater percent of obsolescence, a higher mean initial and last serum creatinine and proteinuria than normotensives. However proteinuria prognosis improved more among hypertensives mostly due to installation of higher doses of ACEls and antihypertensives. Prevalence of HTN
was PGN 800/0, focal PGN 66.6%.