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العنوان
Synthesis Of Some Thiazole Derivatives As Potential Antimicrobial Agents =
الناشر
Hesham Tawfik Youssef Fahmy,
المؤلف
Fahmy, Hesham Tawfik Youssef.
هيئة الاعداد
باحث / هشام توفيق يوسف
مشرف / سامية محمد رضا
مشرف / على احمد
مشرف / السيد احمد بدوى
الموضوع
Pharmaceutical Chemistry.
تاريخ النشر
1990
عدد الصفحات
141 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/1990
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - Pharmaceutical Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

It has been well documented that compounds having thiazole nucleus In their structure possess antineoplastic, antiviral, antibacterial, antitubercular, antifungal and antiparasitic activities. Consequently, a study was initiated to synthesize a wide variety of forty six new compounds having a thiazole nucleus, either linked to another heterocyclic ring known to possess an antimicrobial activity as benzimidazole, or fused with pyrimidine ring to form thiazolo(4,5—djpyrimidine fused—ring system which can be considered as a purine antagonist. These compounds were screened for their in vitro anti—Human Immunodeficiency Virus (HIV) and antimicrobial potencies. The thesis comprises the following:
INTRODUCTION:
It covers a survey of antineoplastic, antiviral, antibacterial, antitubercular, antifungal and antiparasitic activities associated with thiazoles and fused thiazole derivatives and referring to the structure—activity relationship whenever possible.
RESEARCH OBJRCTIVES:
It deals with the aim and bases on which the prepared compounds have been designed.