الفهرس | Only 14 pages are availabe for public view |
Abstract This study was aiming to: 1- Compare changes in Doppler flow velocity waveforms (FVWs), in different fetoplacental vessels (uteroplacental circulation, umbilical artery, fetal middle cerebral artery, fetal descending aorta, and fetal renal artery) in normal pregnancy with those obtained in patients with pre-eclampsia (PE), mild or severe, with or without intrauterine growth retardation (IUGR). 2- Compare between Doppler velocimetry (DV) and fetal biophysical profile (BPP) in prediction of adverse prenatal outcome. The present study concluded that: 1- In normal pregnancy, FVWs from the uterine artery, UA and MCA showed gradual increase in the end-diastolic flow with subsequent decline in Doppler indices. However these changes were less apparent in FDA and fetal RA. 2- Doppler indices of the uterine artery, UA, fetal MCA, FDA, and fetal RA are significantly higher in PE than mild PE. The fetal MCA was the only one of the studied vessels showing lower Doppler indices in PE than in normal pregnancy. 3- Umbilical artery DV is a useful diagnostic tool to assess fetal wellbeing in PE. It should be a useful adjunct to the current methods of fetal surveillance. 4- Absent end-diastolic flow and REDF in the UAFVWs could be considered an ominous sign of IUFD. Immediate delivery is indicated in mature fetus and daily fetal surveillance tests are recommended in immature ones. 5- In pre-eclamptic patients with oligohydramnios, UADV should be performed as it may affect the obstetric management of these cases. Association of oligohydramnios with abnormal UADV selects a group of patients at great risk of intrapartum fetal distress. |