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العنوان
Autologous Crafting in Treatment of Leukoderma /
الناشر
Sherif Shoukry Awad,
المؤلف
Awad, Sherif Shoukry
هيئة الاعداد
باحث / شريف شكرى عوض لطف الله
مشرف / محمد هاني التونسي
مشرف / تاج الدين السيد عنبر
مشرف / معتز بالله مصطفى الدمياطي
مشرف / فاطمة يوسف صالح
الموضوع
Dermatology, STDs & Andrology Leukoderma
تاريخ النشر
2002 .
عدد الصفحات
160 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأمراض الجلدية
تاريخ الإجازة
1/1/2002
مكان الإجازة
جامعة المنيا - كلية الطب - الجلدية والتناسلية
الفهرس
Only 14 pages are availabe for public view

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from 174

Abstract

The of this work is to apply these techniques as new promising tools, and to evaluate the response after treatment with the autologous grafting procedures, in those patients presenting with resistant leukoderma, that failed to respond to the usual styles of therapy. Hoping to provide a new prospect in the treatment of the resistant while patches; the patients in our locality, with racially pigmented skin; are in bad need for.
The best results were obtained in patients receiving dermabrasion and split thickness grafts, where only 5% of the cases got poor results, while 35% of dermabrasion And roof blister graft cases and 40% of those who had minipunch graftinf, got poor results and failure.
The autografting procedure depends upon providing new melanocytes, instead of those dysfunctioning or absent, from normal skin of the patient and transplanting them onto the leukoderma patches in the same patient.
In order to get the best required results, avoidance of infection is mandatory to keep the grafts in position, and this can be achieved through proper disinfection during the procedure and the use of antibiotics. Maintaining the graft in good apposition with the recipient area is also mandatory in the first 2 weeks and the use of sutures and proper dressings is important when contact or movements at or near the grafted areas can not be prevented.
It is recommended to perform test area prior to the whole procedure of minigrafting, in order to those the proper candidate and to get the best results.
In cases with post-burn leukoderma, all cases with deep burn or apparent skin atrophy or scarring should be excluded from these procedures, as no proper recipient bed will be available.
All patients with active keobner phenomenon must be excluded. The development of new lesions of vitiligo will be inevitable at the donor area and recurrence at the recipient site should be anticipated.
The proper choice of patients and the efficiency in the use of those procedures will provide a real new prospect for treating resistant leukoderma.
Aurtografting will help in the management of the arduous puzzle of the depigmented
Patches, especially to those lesions on exposed skin, which add many psychological and social problems in patients in our locality, with dark skin and and the high contrast of colour, between normal skin and leukoderma patches.