Search In this Thesis
   Search In this Thesis  
العنوان
Activated Protein C Resistance in Association with Repeated Miscarriage /
الناشر
Mervat Abdel-Aal Mohamed,
المؤلف
Mohamed, Mervat Abdel-Aal.
هيئة الاعداد
باحث / مرفت عبد العال محمد خير الله
مشرف / زينب أحمد اسماعيل
مشرف / عصمت عبد العزيز عبد اللطيف الشرقاوى
الموضوع
Clinical Pathology - Association with Repeated Miscarriage - Protein C . Hemostasis during Normal Pregnancy -
تاريخ النشر
1999 .
عدد الصفحات
160 p.;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأمراض والطب الشرعي
تاريخ الإجازة
1/1/1999
مكان الإجازة
جامعة المنيا - كلية الطب - علم الأمراض
الفهرس
Only 14 pages are availabe for public view

from 178

from 178

Abstract

Aim of the work
To define the relation of activated protein C resistance (APC-R) to repeated miscarriage.
Conclusion
1- The presence of Toxoplasma IgG antibodies is a common laboratory finding among our referral population; it is most probably a cause of repeated miscarriage especially, in relation to abortion of first trimester and at high dilution.
2- from this study we can be concluded that APC-R which predispose to thrombosis is a cause of recurrent miscarriage but the statistical power of the study is too low to detect the size of the problem and large prospective studies is needed to confirm these finding in the future, also the determination of APC-R must be include both coagulation based function assay and DNA based genetic assay as the information provided the each method is complementary.
3- These findings have important implications for therapy and provide a rationale for clinical trials of thromboprophylaxis for affected women with recurrent fetal loss in subsequent pregnancies.