الفهرس 
ErythropoietinOnly 14 pages are availabe for public view
 |  | from | 156 |  |  |
| | | from | 156 | | |
Abstract
Heavy proteinuria leads to profound alteration of protein metabolism in both clinical and experimental nephrosis. As a results marked canges of plasma concentrations of various may occur.
Erythropoietin is produced by the kidney and is the principle tropic factor for erythrocyte progenitors, hypoxia increases the production of the hormone, which enhances the manufacture of new RBCs.
Te current study was undertaken to to determine the effect of nephritic syndrome on erythropoietin metabolism.
We measured the EPO concentration in plasma and urine of 25 children wit nephritic syndrome by radio immune. The results were compared wit those obtained in a group of 10 normal control children.
Despite a significant reduction in the hemoglobin concentration in te nephritic syndrome group compared with normal control group.