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العنوان
A Comparative Study of the Haemodynamic Effects of Doxacurium Chloride and Pancuronium in Patients Udergoing Open Heart Surgery for Mitral Valve Replacment /
الناشر
Mamdouh A. M.Magid,
المؤلف
Magid, Mamdouh A. M.
هيئة الاعداد
باحث / Mamdouh A. M.Magid
مشرف / Salah EL Khatib
مشرف / Fawzeyia M. Abou EL Fetouh
مشرف / Ibrahim Abbass Yossef
مشرف / Ibrahim Talaat Ibrahim
الموضوع
Anaesthesia - Cardio Vascular Physiological Considerations - Patho Physiology of the Mitral Valve Disease - Haemodynamic Monitoring Of the Cardiac Surgical Patients - Neuromuscular Physiology - Pharmacology -
تاريخ النشر
1996 .
عدد الصفحات
231 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/1996
مكان الإجازة
جامعة المنيا - كلية الطب - Anaesthesiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Aim of the work
To assess the homodynamic response of doxacurium chloride and compare it with that of pancuronium bromide in patients undergoing open heart surgery for mitral valve replacement being among the most frequent open heart surgeries in Egypt.
Conclusion
This study showed that doxacurium chloride has no clinically significant effect on measured or calculated homodynamic variables. Its autonomic margin of safety seems to be wide; in addition, its duration of action is very long.
This combination of a long duration of action and absence of circulatory effects makes it very useful in patients with valvular heart disease undergoing prolonged operations. It seems to be the ideal alternative of pancuronium in cardiac surgery.
Recommendations
We recommend the use of doxacurium chloride instead of pancuronium which causes significant homodynamic response- safely in open heart surgery for patients with mitral valve disease.