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Abstract A total number of 103 cattle (96 adult 3-5 years and 7 calves under one year old) of both sexes were examined in this study. All animals in this study were subjected for clinical and laboratory investigations. Fecal examination, hematological studies and serum biochemical analysis for Fe, Cu, vitamins C and E were carried out. Clinical examination of all investegated animals revealed various diseased conditions such as coccidiosis, babesiosis, Theileria infection ticks infestation and TRP. Qualitative fecal examination of anemic cattle with poor body condition and rough hair was positive for eggs of Trichostrongylidae spp. The quantitative egg count indicates moderate infection (600-1000 egg/gm faeces). Hematological studies of examined animals revealed normocytic hypochromic anemia in cases of Trichostrongylidae infection, coccidiosis, ticks infestation, theileriasis and TRP while it was microcytic normochromic in cases of babesiosis. Leukocytosis was observed in cases of Trichostrongylaide, coccidiosis, babesiosis and TRP, while leukopenia was detected in cases of ticks infestation and Theileria infection. Serum biochemical analysis of examined animals indicates significant reduction in serum ferrous and copper in cases of Trichostrongylidae infection, coccidiosis, ticks infestation, theileriasis and TRP, while their levels were significantly in cattle infected with Babesia spp. Serum biochemical analysis of all diseased animals indicates significant decrease in serum levels of vitamins C and E. The highest reduction in serum level of vitamin E was associated with highest reduction in Fe in anemic cattle infected with theileriasis. The highest reduction in serum level of vitamin C was related to anemia due tick infestation. It can be concluded that: Changes in blood picture in anemic cattle are closely related to the etiological agent. The changes in serum levels of Fe, Cu, vitamin C and vitamin E are related to the causative agent of the anemia. All types of studied anemia are associated with reduction in the serum levels of vitamins C& E. Therefore it can recommend that the therapeutic treatment of anemia should be directed to the cause of anemia. Therapy of anemic condition should involve improving of immune status of the body through supplementation with vitamins C& E. in addition supplementation with adequate amount of Fe and Cu. |