الفهرس 
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Abstract
1- The incidence of Campylobacter jejuni infection in chickens of different ages , non— fertile eggs and dead—in-shell embryos was investigated
2- In this work, 740 samples (‘200” baby chicks • “350’ broi lez, 1 90’ laying birds ) were examined bacteriologically and resulted in the recovery of ‘14” Campylobacter isolates with an incidence of 1.89 % The isolated “14’ strains proved morphologically and biochemically to be Campylobacter jejuni
3— These fourteen C.jejuni isolates were recovered as follows: “ Eight “ from broilers at a rate of 2.3 % and ‘six” frau laying hens in an incidence of
3.2 %
4- Campylobacter spp. were not found in baby chicks, non-fertile eggs or dead embryos
5— Experimental infections of young ( one - week — old ) and older ( 4—week— old ) chicks with C.jejuni via oral and intranasal mutes revealed that
a- The inoculated C.jejuni was pathogenic to one week old and four weeks old chicks
b—The oral route of infection resulted in 52 % and 32 % in one week old and 4 weeks old respectively , whereas the intranasal route of infection produced 36% mortality rate in one week old and 20% mortality rate in four weeks old chicks
c- The young birds vre more susceptible and showed higher mortality rate than the older ones
d— The oral route of infection was more effective with high mortality rate in comparison with the intranasal one 6- Experimental infections in chicken embryos showed that
a— Campylobacter jejuni was highly virulent to embryos via the yolk sac
route of inoculation with zero % hatchability rate
b- Immersion of chicken embryos in suspension of C.jejuni resulted in hatchability rate of 73.3 %
7- According to the results of no recovery of the organism from baby chicks, non fertile eggs, and dead in shell embryos as well as the results of immersion of chicken embryos in C.jejuni suspension, it is concluded that , transmission of the organism to hatched chicks via eggs is highly improbabTh
8— The clinical signs and macroniorphological changes in naturally and
artificially infected birds were recorded and discussed
9— AU Canipylobacter jejuni isolates from chicken in this work were sensitive in vitro to gentarnycin , flumequine , nalidixic acid , neomycin and chlortetracycline.