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Abstract
Perfusion CT was introduced to help identify and quantify the presence and extent of a perfusion deficit in patients presenting with acute stroke symptoms. The level of perfusion to the ischemic tissues may help to determine the relative benefits and risks of a given therapy.
Perfusion CT quickly monitors the contrast agent through the cerebral
vasculature with any standard spiral CT scanner. Changes in tissue attenuation that occur in the brain are measured after the contrast injection.
Post-processing of the perfusion CT data allows the generation of colorcoded
maps of various perfusion parameters, including cerebral blood flow
(CBF), cerebral blood volume (CBV), mean transit time (MTT), and the
time-to-peak (TTP), the time from the start of contrast agent injection to the
time of maximum enhancement. Perfusion CT scan may become part of the
screening CT protocol in the future.