Search In this Thesis
   Search In this Thesis  
العنوان
comparative studies on the healing process of some nerves in donkeys following anastomosis with some suture materials/
المؤلف
Seeha, Samir Melad.
هيئة الاعداد
باحث / Samir Melad Seeha
مشرف / Abdel-Latef Hassan Bayoumi
مناقش / Mohamed Abdel-Tawab
مناقش / Abdel-Rehem Amen Nagy
الموضوع
Vetrinary Medicine.
تاريخ النشر
1999.
عدد الصفحات
164 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Veterinary (miscellaneous)
الناشر
تاريخ الإجازة
27/9/1999
مكان الإجازة
جامعة أسيوط - كلية الطب البيطري - جراحة حيوان
الفهرس
Only 14 pages are availabe for public view

from 184

from 184

Abstract

Sumnlary
The present work was carried on 32 donkeys. The work was t of two parts. The first part was carried on 24 young aged donkeys. econd PaIt was carried on 8 adult aged donkeys.
In the first part, to evaluate the influence of suture materials and ’ques on regenration of ulnar and tibial nerves, 24 donkeys were d into four equal groups. In each donkey, four experimental tions were done 011 both ulnar and both tibial nerves. In all groups,
nerve was exposed and severed and the deinnervated area was ined.
the first group (control group), the severed nerves were left without stomosis.
he second group, the severed nerves were anastomosed by using 6/0
he third group, the severed nerves were anastomosed by using 6/0 on-Puis.
he fourth group, the severed nerves were anastomosed by using 6/0 ted- Vicryl.
According to the techniques of anastomosis, the 2nd, 3rd and 4th were divided into two sub-groups. In the first sub-group, epineurial technique was used and in tIle secund sub-brroup, epineurial splint ue W(lS used. In each donkey, Epineurial spliM technique was used It limbs and Epineurial suture technique vVClS used for left limbs.





145
The healing process of the ulnar and tibial nerves were evaluated on basis of clinical and histopathological results. Clinical evaluation on retlml of sensation in the desensitized skin areas.
opathological evaluation depends on the regeneration ofaxons, ann cells and also the aJ.llOlmt of fibrosis at the site of anastomosis.
In the second part, 8 adult aged donkeys were divided”into two al groups.
le first group, the dorsal buccal nerve was exposed and severed.
le second group, the radial nerve was exposed and severed.
In the two groups, nerve anastomosis was performed using
ineurial splint technique and 6/0 Coated- Vicryl.
r results were as the following:
The first part:
In the first group, (control group), the clinical evaluation revealed that
no return of sensation to the desensitized skin areas. The histopathological examination indicated that sever lysis ofaxol1s, distortion of nerve fascicles and sever fibrosis at site of anastomosis.
In the second group, the clil1ical evaluation revealed that the sensation began to return• in the desensitized skin areas at the end of 13th week post-operation in some donkeys in hind limbs and at the end of 14th week in forel limbs’ respectively. The histopathological evaluation indicated massive fibrosis infiltrated the epineurium, perineurium and
silk fibrils at the site of anastomosis.
) In the third group, the clinical evaluation revealed that the sensation
began to return in the desensitized skin areas LIt the end of 6th week post-operation in some donkeys in hind limbs and (It the end of 7th




146
:k in fore limbs respectively. The histopathological evaluation ~aled that most of nerve fascicles contains distinct axons and
lwann cells. Moderat fibrosis was distinct in epineurium and
the fourth group, the clinical evaluation revealed that the sensation san to return in the desensitized skin areas at the end of 4th week st-operation in some donkeys in fore and and hind limbs. The histo¬lhological evaluation indicated that the nerve fascicles had the rnal structural elements and slight fibrous connective tissue invaded e epineurium and perineurium at the site of anastomosis.
The healing evaluation of the anastomosed dorsal buccal and radial s were evaluated on the basis of speed and completeness of the return
tor function to the affected areas.
Our cliilical results indicated that the healing process of the dorsal I and radial nerves was successful and in some donkeys the motor on of dorsal buccal and radial nerves were returl1L.,(l at the end of 4th
. -
post-operation.
In the present work, - we can concluded that for repair of the ulnar, , dorsal buccal and radial nerves, •the Coated- Vicryl and Epinemial t technique were more successful than Dexon, Silk and Epineurial
e technique.


Sumnlary
The present work was carried on 32 donkeys. The work was t of two parts. The first part was carried on 24 young aged donkeys. econd PaIt was carried on 8 adult aged donkeys.
In the first part, to evaluate the influence of suture materials and ’ques on regenration of ulnar and tibial nerves, 24 donkeys were d into four equal groups. In each donkey, four experimental tions were done 011 both ulnar and both tibial nerves. In all groups,
nerve was exposed and severed and the deinnervated area was ined.
the first group (control group), the severed nerves were left without stomosis.
he second group, the severed nerves were anastomosed by using 6/0
he third group, the severed nerves were anastomosed by using 6/0 on-Puis.
he fourth group, the severed nerves were anastomosed by using 6/0 ted- Vicryl.
According to the techniques of anastomosis, the 2nd, 3rd and 4th were divided into two sub-groups. In the first sub-group, epineurial technique was used and in tIle secund sub-brroup, epineurial splint ue W(lS used. In each donkey, Epineurial spliM technique was used It limbs and Epineurial suture technique vVClS used for left limbs.





145
The healing process of the ulnar and tibial nerves were evaluated on basis of clinical and histopathological results. Clinical evaluation on retlml of sensation in the desensitized skin areas.
opathological evaluation depends on the regeneration ofaxons, ann cells and also the aJ.llOlmt of fibrosis at the site of anastomosis.
In the second part, 8 adult aged donkeys were divided”into two al groups.
le first group, the dorsal buccal nerve was exposed and severed.
le second group, the radial nerve was exposed and severed.
In the two groups, nerve anastomosis was performed using
ineurial splint technique and 6/0 Coated- Vicryl.
r results were as the following:
The first part:
In the first group, (control group), the clinical evaluation revealed that
no return of sensation to the desensitized skin areas. The histopathological examination indicated that sever lysis ofaxol1s, distortion of nerve fascicles and sever fibrosis at site of anastomosis.
In the second group, the clil1ical evaluation revealed that the sensation began to return• in the desensitized skin areas at the end of 13th week post-operation in some donkeys in hind limbs and at the end of 14th week in forel limbs’ respectively. The histopathological evaluation indicated massive fibrosis infiltrated the epineurium, perineurium and
silk fibrils at the site of anastomosis.
) In the third group, the clinical evaluation revealed that the sensation
began to return in the desensitized skin areas LIt the end of 6th week post-operation in some donkeys in hind limbs and (It the end of 7th




146
:k in fore limbs respectively. The histopathological evaluation ~aled that most of nerve fascicles contains distinct axons and
lwann cells. Moderat fibrosis was distinct in epineurium and
the fourth group, the clinical evaluation revealed that the sensation san to return in the desensitized skin areas at the end of 4th week st-operation in some donkeys in fore and and hind limbs. The histo¬lhological evaluation indicated that the nerve fascicles had the rnal structural elements and slight fibrous connective tissue invaded e epineurium and perineurium at the site of anastomosis.
The healing evaluation of the anastomosed dorsal buccal and radial s were evaluated on the basis of speed and completeness of the return
tor function to the affected areas.
Our cliilical results indicated that the healing process of the dorsal I and radial nerves was successful and in some donkeys the motor on of dorsal buccal and radial nerves were returl1L.,(l at the end of 4th
. -
post-operation.
In the present work, - we can concluded that for repair of the ulnar, , dorsal buccal and radial nerves, •the Coated- Vicryl and Epinemial t technique were more successful than Dexon, Silk and Epineurial
e technique.


Sumnlary
The present work was carried on 32 donkeys. The work was t of two parts. The first part was carried on 24 young aged donkeys. econd PaIt was carried on 8 adult aged donkeys.
In the first part, to evaluate the influence of suture materials and ’ques on regenration of ulnar and tibial nerves, 24 donkeys were d into four equal groups. In each donkey, four experimental tions were done 011 both ulnar and both tibial nerves. In all groups,
nerve was exposed and severed and the deinnervated area was ined.
the first group (control group), the severed nerves were left without stomosis.
he second group, the severed nerves were anastomosed by using 6/0
he third group, the severed nerves were anastomosed by using 6/0 on-Puis.
he fourth group, the severed nerves were anastomosed by using 6/0 ted- Vicryl.
According to the techniques of anastomosis, the 2nd, 3rd and 4th were divided into two sub-groups. In the first sub-group, epineurial technique was used and in tIle secund sub-brroup, epineurial splint ue W(lS used. In each donkey, Epineurial spliM technique was used It limbs and Epineurial suture technique vVClS used for left limbs.





145
The healing process of the ulnar and tibial nerves were evaluated on basis of clinical and histopathological results. Clinical evaluation on retlml of sensation in the desensitized skin areas.
opathological evaluation depends on the regeneration ofaxons, ann cells and also the aJ.llOlmt of fibrosis at the site of anastomosis.
In the second part, 8 adult aged donkeys were divided”into two al groups.
le first group, the dorsal buccal nerve was exposed and severed.
le second group, the radial nerve was exposed and severed.
In the two groups, nerve anastomosis was performed using
ineurial splint technique and 6/0 Coated- Vicryl.
r results were as the following:
The first part:
In the first group, (control group), the clinical evaluation revealed that
no return of sensation to the desensitized skin areas. The histopathological examination indicated that sever lysis ofaxol1s, distortion of nerve fascicles and sever fibrosis at site of anastomosis.
In the second group, the clil1ical evaluation revealed that the sensation began to return• in the desensitized skin areas at the end of 13th week post-operation in some donkeys in hind limbs and at the end of 14th week in forel limbs’ respectively. The histopathological evaluation indicated massive fibrosis infiltrated the epineurium, perineurium and
silk fibrils at the site of anastomosis.
) In the third group, the clinical evaluation revealed that the sensation
began to return in the desensitized skin areas LIt the end of 6th week post-operation in some donkeys in hind limbs and (It the end of 7th




146
:k in fore limbs respectively. The histopathological evaluation ~aled that most of nerve fascicles contains distinct axons and
lwann cells. Moderat fibrosis was distinct in epineurium and
the fourth group, the clinical evaluation revealed that the sensation san to return in the desensitized skin areas at the end of 4th week st-operation in some donkeys in fore and and hind limbs. The histo¬lhological evaluation indicated that the nerve fascicles had the rnal structural elements and slight fibrous connective tissue invaded e epineurium and perineurium at the site of anastomosis.
The healing evaluation of the anastomosed dorsal buccal and radial s were evaluated on the basis of speed and completeness of the return
tor function to the affected areas.
Our cliilical results indicated that the healing process of the dorsal I and radial nerves was successful and in some donkeys the motor on of dorsal buccal and radial nerves were returl1L.,(l at the end of 4th
. -
post-operation.
In the present work, - we can concluded that for repair of the ulnar, , dorsal buccal and radial nerves, •the Coated- Vicryl and Epinemial t technique were more successful than Dexon, Silk and Epineurial
e technique.


Sumnlary
The present work was carried on 32 donkeys. The work was t of two parts. The first part was carried on 24 young aged donkeys. econd PaIt was carried on 8 adult aged donkeys.
In the first part, to evaluate the influence of suture materials and ’ques on regenration of ulnar and tibial nerves, 24 donkeys were d into four equal groups. In each donkey, four experimental tions were done 011 both ulnar and both tibial nerves. In all groups,
nerve was exposed and severed and the deinnervated area was ined.
the first group (control group), the severed nerves were left without stomosis.
he second group, the severed nerves were anastomosed by using 6/0
he third group, the severed nerves were anastomosed by using 6/0 on-Puis.
he fourth group, the severed nerves were anastomosed by using 6/0 ted- Vicryl.
According to the techniques of anastomosis, the 2nd, 3rd and 4th were divided into two sub-groups. In the first sub-group, epineurial technique was used and in tIle secund sub-brroup, epineurial splint ue W(lS used. In each donkey, Epineurial spliM technique was used It limbs and Epineurial suture technique vVClS used for left limbs.





145
The healing process of the ulnar and tibial nerves were evaluated on basis of clinical and histopathological results. Clinical evaluation on retlml of sensation in the desensitized skin areas.
opathological evaluation depends on the regeneration ofaxons, ann cells and also the aJ.llOlmt of fibrosis at the site of anastomosis.
In the second part, 8 adult aged donkeys were divided”into two al groups.
le first group, the dorsal buccal nerve was exposed and severed.
le second group, the radial nerve was exposed and severed.
In the two groups, nerve anastomosis was performed using
ineurial splint technique and 6/0 Coated- Vicryl.
r results were as the following:
The first part:
In the first group, (control group), the clinical evaluation revealed that
no return of sensation to the desensitized skin areas. The histopathological examination indicated that sever lysis ofaxol1s, distortion of nerve fascicles and sever fibrosis at site of anastomosis.
In the second group, the clil1ical evaluation revealed that the sensation began to return• in the desensitized skin areas at the end of 13th week post-operation in some donkeys in hind limbs and at the end of 14th week in forel limbs’ respectively. The histopathological evaluation indicated massive fibrosis infiltrated the epineurium, perineurium and
silk fibrils at the site of anastomosis.
) In the third group, the clinical evaluation revealed that the sensation
began to return in the desensitized skin areas LIt the end of 6th week post-operation in some donkeys in hind limbs and (It the end of 7th




146
:k in fore limbs respectively. The histopathological evaluation ~aled that most of nerve fascicles contains distinct axons and
lwann cells. Moderat fibrosis was distinct in epineurium and
the fourth group, the clinical evaluation revealed that the sensation san to return in the desensitized skin areas at the end of 4th week st-operation in some donkeys in fore and and hind limbs. The histo¬lhological evaluation indicated that the nerve fascicles had the rnal structural elements and slight fibrous connective tissue invaded e epineurium and perineurium at the site of anastomosis.
The healing evaluation of the anastomosed dorsal buccal and radial s were evaluated on the basis of speed and completeness of the return
tor function to the affected areas.
Our cliilical results indicated that the healing process of the dorsal I and radial nerves was successful and in some donkeys the motor on of dorsal buccal and radial nerves were returl1L.,(l at the end of 4th
. -
post-operation.
In the present work, - we can concluded that for repair of the ulnar, , dorsal buccal and radial nerves, •the Coated- Vicryl and Epinemial t technique were more successful than Dexon, Silk and Epineurial
e technique.


Sumnlary
The present work was carried on 32 donkeys. The work was t of two parts. The first part was carried on 24 young aged donkeys. econd PaIt was carried on 8 adult aged donkeys.
In the first part, to evaluate the influence of suture materials and ’ques on regenration of ulnar and tibial nerves, 24 donkeys were d into four equal groups. In each donkey, four experimental tions were done 011 both ulnar and both tibial nerves. In all groups,
nerve was exposed and severed and the deinnervated area was ined.
the first group (control group), the severed nerves were left without stomosis.
he second group, the severed nerves were anastomosed by using 6/0
he third group, the severed nerves were anastomosed by using 6/0 on-Puis.
he fourth group, the severed nerves were anastomosed by using 6/0 ted- Vicryl.
According to the techniques of anastomosis, the 2nd, 3rd and 4th were divided into two sub-groups. In the first sub-group, epineurial technique was used and in tIle secund sub-brroup, epineurial splint ue W(lS used. In each donkey, Epineurial spliM technique was used It limbs and Epineurial suture technique vVClS used for left limbs.





145
The healing process of the ulnar and tibial nerves were evaluated on basis of clinical and histopathological results. Clinical evaluation on retlml of sensation in the desensitized skin areas.
opathological evaluation depends on the regeneration ofaxons, ann cells and also the aJ.llOlmt of fibrosis at the site of anastomosis.
In the second part, 8 adult aged donkeys were divided”into two al groups.
le first group, the dorsal buccal nerve was exposed and severed.
le second group, the radial nerve was exposed and severed.
In the two groups, nerve anastomosis was performed using
ineurial splint technique and 6/0 Coated- Vicryl.
r results were as the following:
The first part:
In the first group, (control group), the clinical evaluation revealed that
no return of sensation to the desensitized skin areas. The histopathological examination indicated that sever lysis ofaxol1s, distortion of nerve fascicles and sever fibrosis at site of anastomosis.
In the second group, the clil1ical evaluation revealed that the sensation began to return• in the desensitized skin areas at the end of 13th week post-operation in some donkeys in hind limbs and at the end of 14th week in forel limbs’ respectively. The histopathological evaluation indicated massive fibrosis infiltrated the epineurium, perineurium and
silk fibrils at the site of anastomosis.
) In the third group, the clinical evaluation revealed that the sensation
began to return in the desensitized skin areas LIt the end of 6th week post-operation in some donkeys in hind limbs and (It the end of 7th




146
:k in fore limbs respectively. The histopathological evaluation ~aled that most of nerve fascicles contains distinct axons and
lwann cells. Moderat fibrosis was distinct in epineurium and
the fourth group, the clinical evaluation revealed that the sensation san to return in the desensitized skin areas at the end of 4th week st-operation in some donkeys in fore and and hind limbs. The histo¬lhological evaluation indicated that the nerve fascicles had the rnal structural elements and slight fibrous connective tissue invaded e epineurium and perineurium at the site of anastomosis.
The healing evaluation of the anastomosed dorsal buccal and radial s were evaluated on the basis of speed and completeness of the return
tor function to the affected areas.
Our cliilical results indicated that the healing process of the dorsal I and radial nerves was successful and in some donkeys the motor on of dorsal buccal and radial nerves were returl1L.,(l at the end of 4th
. -
post-operation.
In the present work, - we can concluded that for repair of the ulnar, , dorsal buccal and radial nerves, •the Coated- Vicryl and Epinemial t technique were more successful than Dexon, Silk and Epineurial
e technique.


Sumnlary
The present work was carried on 32 donkeys. The work was t of two parts. The first part was carried on 24 young aged donkeys. econd PaIt was carried on 8 adult aged donkeys.
In the first part, to evaluate the influence of suture materials and ’ques on regenration of ulnar and tibial nerves, 24 donkeys were d into four equal groups. In each donkey, four experimental tions were done 011 both ulnar and both tibial nerves. In all groups,
nerve was exposed and severed and the deinnervated area was ined.
the first group (control group), the severed nerves were left without stomosis.
he second group, the severed nerves were anastomosed by using 6/0
he third group, the severed nerves were anastomosed by using 6/0 on-Puis.
he fourth group, the severed nerves were anastomosed by using 6/0 ted- Vicryl.
According to the techniques of anastomosis, the 2nd, 3rd and 4th were divided into two sub-groups. In the first sub-group, epineurial technique was used and in tIle secund sub-brroup, epineurial splint ue W(lS used. In each donkey, Epineurial spliM technique was used It limbs and Epineurial suture technique vVClS used for left limbs.





145
The healing process of the ulnar and tibial nerves were evaluated on basis of clinical and histopathological results. Clinical evaluation on retlml of sensation in the desensitized skin areas.
opathological evaluation depends on the regeneration ofaxons, ann cells and also the aJ.llOlmt of fibrosis at the site of anastomosis.
In the second part, 8 adult aged donkeys were divided”into two al groups.
le first group, the dorsal buccal nerve was exposed and severed.
le second group, the radial nerve was exposed and severed.
In the two groups, nerve anastomosis was performed using
ineurial splint technique and 6/0 Coated- Vicryl.
r results were as the following:
The first part:
In the first group, (control group), the clinical evaluation revealed that
no return of sensation to the desensitized skin areas. The histopathological examination indicated that sever lysis ofaxol1s, distortion of nerve fascicles and sever fibrosis at site of anastomosis.
In the second group, the clil1ical evaluation revealed that the sensation began to return• in the desensitized skin areas at the end of 13th week post-operation in some donkeys in hind limbs and at the end of 14th week in forel limbs’ respectively. The histopathological evaluation indicated massive fibrosis infiltrated the epineurium, perineurium and
silk fibrils at the site of anastomosis.
) In the third group, the clinical evaluation revealed that the sensation
began to return in the desensitized skin areas LIt the end of 6th week post-operation in some donkeys in hind limbs and (It the end of 7th




146
:k in fore limbs respectively. The histopathological evaluation ~aled that most of nerve fascicles contains distinct axons and
lwann cells. Moderat fibrosis was distinct in epineurium and
the fourth group, the clinical evaluation revealed that the sensation san to return in the desensitized skin areas at the end of 4th week st-operation in some donkeys in fore and and hind limbs. The histo¬lhological evaluation indicated that the nerve fascicles had the rnal structural elements and slight fibrous connective tissue invaded e epineurium and perineurium at the site of anastomosis.
The healing evaluation of the anastomosed dorsal buccal and radial s were evaluated on the basis of speed and completeness of the return
tor function to the affected areas.
Our cliilical results indicated that the healing process of the dorsal I and radial nerves was successful and in some donkeys the motor on of dorsal buccal and radial nerves were returl1L.,(l at the end of 4th
. -
post-operation.
In the present work, - we can concluded that for repair of the ulnar, , dorsal buccal and radial nerves, •the Coated- Vicryl and Epinemial t technique were more successful than Dexon, Silk and Epineurial
e technique.


Sumnlary
The present work was carried on 32 donkeys. The work was t of two parts. The first part was carried on 24 young aged donkeys. econd PaIt was carried on 8 adult aged donkeys.
In the first part, to evaluate the influence of suture materials and ’ques on regenration of ulnar and tibial nerves, 24 donkeys were d into four equal groups. In each donkey, four experimental tions were done 011 both ulnar and both tibial nerves. In all groups,
nerve was exposed and severed and the deinnervated area was ined.
the first group (control group), the severed nerves were left without stomosis.
he second group, the severed nerves were anastomosed by using 6/0
he third group, the severed nerves were anastomosed by using 6/0 on-Puis.
he fourth group, the severed nerves were anastomosed by using 6/0 ted- Vicryl.
According to the techniques of anastomosis, the 2nd, 3rd and 4th were divided into two sub-groups. In the first sub-group, epineurial technique was used and in tIle secund sub-brroup, epineurial splint ue W(lS used. In each donkey, Epineurial spliM technique was used It limbs and Epineurial suture technique vVClS used for left limbs.





145
The healing process of the ulnar and tibial nerves were evaluated on basis of clinical and histopathological results. Clinical evaluation on retlml of sensation in the desensitized skin areas.
opathological evaluation depends on the regeneration ofaxons, ann cells and also the aJ.llOlmt of fibrosis at the site of anastomosis.
In the second part, 8 adult aged donkeys were divided”into two al groups.
le first group, the dorsal buccal nerve was exposed and severed.
le second group, the radial nerve was exposed and severed.
In the two groups, nerve anastomosis was performed using
ineurial splint technique and 6/0 Coated- Vicryl.
r results were as the following:
The first part:
In the first group, (control group), the clinical evaluation revealed that
no return of sensation to the desensitized skin areas. The histopathological examination indicated that sever lysis ofaxol1s, distortion of nerve fascicles and sever fibrosis at site of anastomosis.
In the second group, the clil1ical evaluation revealed that the sensation began to return• in the desensitized skin areas at the end of 13th week post-operation in some donkeys in hind limbs and at the end of 14th week in forel limbs’ respectively. The histopathological evaluation indicated massive fibrosis infiltrated the epineurium, perineurium and
silk fibrils at the site of anastomosis.
) In the third group, the clinical evaluation revealed that the sensation
began to return in the desensitized skin areas LIt the end of 6th week post-operation in some donkeys in hind limbs and (It the end of 7th




146
:k in fore limbs respectively. The histopathological evaluation ~aled that most of nerve fascicles contains distinct axons and
lwann cells. Moderat fibrosis was distinct in epineurium and
the fourth group, the clinical evaluation revealed that the sensation san to return in the desensitized skin areas at the end of 4th week st-operation in some donkeys in fore and and hind limbs. The histo¬lhological evaluation indicated that the nerve fascicles had the rnal structural elements and slight fibrous connective tissue invaded e epineurium and perineurium at the site of anastomosis.
The healing evaluation of the anastomosed dorsal buccal and radial s were evaluated on the basis of speed and completeness of the return
tor function to the affected areas.
Our cliilical results indicated that the healing process of the dorsal I and radial nerves was successful and in some donkeys the motor on of dorsal buccal and radial nerves were returl1L.,(l at the end of 4th
. -
post-operation.
In the present work, - we can concluded that for repair of the ulnar, , dorsal buccal and radial nerves, •the Coated- Vicryl and Epinemial t technique were more successful than Dexon, Silk and Epineurial
e technique.