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Abstract
It is difficult to detect precancerous lesions such as dysplasia and carcinoma
in situ (CIS) by (WLB) because these lesions are only a few millimeters in
surface diameter. (LIFE) has been reported to detect such lesions more readily, A relatively low specificity because too many false positives remains a problem for AFB, the normal layered structure of the bronchial wall of the central airway as it appears under EBUS has been reported, making it possible to evaluate the early changes that occur in the tracheobronchial tree .In this research we research studied the value of adding EBUS to AFB as an adjuvant procedure to improve specificity of AFB and sensitivity of WLB in detection early lung cancer .the study was carried on 50 patients ,it is
concluded that the sensitivity of AFB+EBUS was 100% and the specificity
was 90.9 , the positive predictive value was 90.9% and the negative predictive value was 100% while the diagnostic accuracy was 95.2 %Combined AFB+EBUS decreased the number of biopsies taken from the false positive lesions examined by AFB alone so increased the specificity the positive predictive value and the diagnostic accuracy .