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Abstract
Intrathecal opioid administration has been demonstrated to provide effective
post-operative analgesia after a variety of surgical procedures at the cost of
increased risk of respiratory depression.
Tramadol, an opioid agonist is known to provide adequate analgesia with
less respiratory depression. Animal studies have confirmed the analgesic effect of
intrathecally administered tramadol but human studies establishing its efficacy are
still lacking.
The present study was carried out to evaluate and study clinically the
efficacy in terms of duration of action and side effects of tramadol 25 mg when
given intrathecally with 0.5% bupivacaine in numbers of lower abdominal
surgeries.
The study was conducted upon 60 patients, less than 55 years old of ASA
and II classification who are operated upon for lower abdominal surgeries.
The patients were randomly divided into 2 equal groups:
Group S: 30 patients received 3 ml bupivacaine 0.5% intrathecally along with 0.5
ml saline.
Group T: 30 patients received 3 ml bupivacaine 0.5% intrathecally along with 0.5
ml (25 mg) tramadol.
In the present study, there was slight statistical significant difference in HR
and BP between the two groups but not clinically significant