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Abstract Our study suggests that PSE is a safe and useful alternative to splenectomy in patients with hypersplenism caused by cirrhosis. PSE can improve severe thrombocytopenia or leucopenia in patients with cirrhosis. However, severe and potentially lethal complications may occur in a significant proportion of patients. Therefore the following guidelines are recommended, careful selection of patients and a ratio of splenic necrosis as close as possible to 50% while close monitoring post procedure with clinical and ultrasound follow-up particularly in patients with a volume of splenic necrosis >50%. |