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المستخلص Scorpion venom is a potent stimulator of the autonomic nervous system causing a sudden outpouring of endogenous catecholamines into the circulation. This leads to transient sympathetic stimulation manifested by vomiting, sweating, bradycardia, priapism, salivation and hypotension. Later sustained parasympathetic stimulation is followed with hypertension, tachycardia, and myocardial failure. Pulmonary edema is the most serious complication of scorpion envenomation and is the usual cause of death in this syndrome. It has been attributed to acute left ventricular failure and increased pulmonary vascular permeability induced by vasoactive substances released upon the venom sting. The aim of this work was to assess the possible role of some laboratory parameters such as plasma proteins, hemoglobin concentration, total leukocytic count and platelet count in early diagnosis of pulmonary edema secondary to scorpion envenomation among patients. This study was done during the period from January 2008 to September 2008.The total number of scorpion sting cases received by the Poison Control Center (PCC) was 193 cases. Out of these 193 cases, 19 patients of both sexes were admitted to the Poison Control Center (PCC) and all of them were enrolled in this study. All these patients had manifestations of Summary 111 scorpion envenomation.In addition ten healthy individuals were used as negative controls. These patients were classified according to the presence of pulmonary edema into two groups; patients without pulmonary edema (group II) and patients with pulmonary edema (group III).The healthy individuals served as controls (group I). The results were tabulated and statistically analyzed and revealed that: Age The mean age in the current study was 21.15±13.98 in group II and 16.40±11.22 in group III, ranging from11m to 48 years. Gender Males represented the majority of cases (63.2%) while females represented (36.8%).In group II ,males were (57.1%) and females were (42.9%) while in group III they were (80%) and (20%) respectively. Residence The majority of cases (63.2%) came from Mansheyt Naser followed by El fayoum (15.8%), Giza (10.5%) and the least number of cases came from Ismailia and Monoufya (5.25%each). |