الفهرس 
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Abstract
The genus Crinum represents an important sector m family Amaryllidaceae with a wide geographical distribution throughout the tropics and warm temperate regions of the world. Besides their popularity as ornamental garden plants with beautiful and elegant flowers, they attracted considerable attention due to various medicinal properties and were subjected to chemical, cytological and pharmacologicai investigations due to their richness in pharmacologically active alkaloids. Part I:
Phytochemical study of Crinum augustum Rox. including: extraction, fractionation, isolation and identification of the main constituents of the bulbs.
Part II:
Phytochemical studies of Crinum asiaticum L. including: investigation of the unsaponifiable matter and fatty acids of the leaves, volatile oil of the flowers, extraction and fractionation of the leaves.
Part III:
Biological study of Crinum augustum Rox. and Crinum asiaticum L., including: determination of the LDso of Crinum augustum Rox., evaluation of the analgesic and anti-inflammatory activities of Crinum augustum Rox., comparative study of the antimicrobial activity of Crinum augustum Rox. and Crinum asiaticum L. and evaluation of the antifouling activity of some compounds isolated from Crinum augustum Rox. bulbs.
The air-dried powdered bulbs (4 Kg) were extracted by maceration with ethanol (95%). The alcohol extract was concentrated under reduced pressure to a syrupy consistency (795 g).
The solvent-free residue was partitioned between 5% HCI and chloroform. The combined chloroform fractions were concentrated under reduced pressure to give fraction I (487 g). The aqueous solution was rendered alkaline with NH40H (T.S) and extracted with chloroform. The combined chloroform fractions were concentrated under reduced pressure to give fraction II (10.3 g). The remaining mother liquor was then re-extracted with several portions of ethyl acetate. The combined ethyl acetate fractions were evaporated under reduced pressure to give fraction III (11.4 g). The resulting mother liquor was saturated with Na2C03 and then re-extracted with chloroform. The combined chloroform fractions were concentrated under reduced pressure to give fraction IV (1.32 g). The remaining mother liquor was evaporated under reduced pressure to give a semisolid viscous residue (408.7 g) that was treated with methanol. The mixture was then filtered and the filtrate were concentrated under reduced pressure to give fraction V (201.5 g).
A part (20 g) of the obtained residue of fraction I was subjected to column chromatographic fractionation on silica gel. Elution was done using; petroleum ether-ethyl acetate (98:2, 95 :5, 90: 10, 70:30 and 50:50) and finally with ethyl acetate.