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Abstract
Diabetes is characterized by hyperglycemia and a markedly diminished insulin function. Over the long term of hyperglycemia generates a large number of free radicals, which induce cell oxidative stress. Oxidative stress from a disturbance in the balance between the formation of free radicals in the body and scavenging of these radicals. These ROS damage
the function of all cell macromolecules and organelles. In physiological
processes, antioxidative enzymes and different antioxidants protect the cells
against harmful free radicals. Thus antioxidant administration would be
beneficial in the treatment of diabetes.
Botanical products such as cinnamon can improve glucose metabolism
and over all condition of persons with diabetes not only by hypoglycemic
effect but also by improving lipid metabolism, antioxidant status, and
capillary function.
The present study was undertaken to investigate the impact of
oxidative stress in diabetes-induced tissue damage in rat. In addition to
investigate if cinnamon can be modulate the oxidative stress -induced by
diabetes mellitus.