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العنوان
Clinico-pathological studies on the effect of exposure of rats to deltamethrin insecticide /
المؤلف
Salib, Venees Farouk Yassa.
هيئة الاعداد
باحث / قينيس فاروق يسّى صليب
مشرف / محمد إبراهيم دسوقي
مشرف / علاء رأفت أحمد
مشرف / هاني حلمي حليم
الموضوع
studies. Rats. Insecticide.
تاريخ النشر
2007.
عدد الصفحات
121 Leaves :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
البيطري
تاريخ الإجازة
1/1/2007
مكان الإجازة
جامعة القاهرة - كلية الطب البيطري - Clinical Pathology
الفهرس
Only 14 pages are availabe for public view

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from 123

Abstract

Study on the effects of repeated exposure to deltamethrin on the blood
picture, certain serum biochemical constituents, bone marrow, semen picture,
histopathological alterations, deltamethrin residues and genotoxic effect in male
albino rat were conducted by Venees Farouk Yassa. Thesis for Ph.D. degree
(Clinical Pathology) Fac. Vet. Med., Cairo University. This study revealed that the
oral the LDsoof deltamethrin was 26.61 mg / kg b.wt .. Repeated oral administertion
of deltamethrin (0.26 mg/kg b.wt.) twice weekly for 180 days resulted in decrease
in RBCs count, Hb concentration, leukocytosis, neutrophilia, lymphocytosis and
increase in MIE ratio. Significant elevation in AL T and AST activities, cholesterol
and urea level. Hyperglycemia followed by hypo glycemia together with a
reduction in testosterone hormone was detected at the end of the experiment.
,.
Semen analysis revealed significant decrease in the sperm cell concentration,
motility percent, together with increase in the percentage of abnormal and dead
sperms. Deltamethrin residue was found in the kidney, liver, muscle and testes.
Furthermore, deltamethrin induce histopathological alteration in the liver, kidney
and testes. In addition to these findings deltamethrin induce significant increase in
the structural chromosomal aberration after 24h. of the first exposure.