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العنوان
Production and characterization of monoclonal antibodies against tuberculosis /
المؤلف
Elsergany, Elham Fadl AbdElhamed Hussien.
هيئة الاعداد
باحث / إلهام فضل عبد الحميد حسين السرجاني
مشرف / كاميليا محمود عثمان أ حمد
مشرف / رقية محمد عثمان محمد
الموضوع
Monoclonal antibodies Diagnostic use. Tuberculosis.
تاريخ النشر
2007.
عدد الصفحات
172 Leaves :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
البيطري
تاريخ الإجازة
1/1/2007
مكان الإجازة
جامعة القاهرة - كلية الطب البيطري - Microbiology
الفهرس
Only 14 pages are availabe for public view

from 188

from 188

Abstract

Tuberculosis considered as a major disease problem in human and veterinary medicine. In this study one monoclonal antibody (MAb) was produced against purified protein derivative of Mycobacterium bovis reacted in Western blot test with a single band of 66 kDa. This MAb was used in competitive ELISA as a diagnostic tool and by comparing the results of competitive ELISA and indirect ELISA it revealed high specificity and sensitivity of competitive ELISA than indirect ELISA which make it a good diagnostic tool for diagnosis of tuberculosis. from the results of this study it is recommend that the development of such a diagnostic tool for diagnosis of bovine tuberculosis for better control of the disease spread and ultimately eradication of the disease with minimum cost.